See Yoshi and Mario
After your battle with Ninja, take a time to look around Otacon's office. You'll see a Yoshi and Mario statue on a filing cabinet. Shoot the Yoshi and he will make his classic noise. Shoot Mario and a 1Up will appear above his head. In addition, you will get a health bonus with each 1Up.
GameCube and Wave Bird
In Otacon's office, take a look at the desk to find a GameCube and Wave Bird. In addition, look at the monitor nearby to see the GameCube boot-up screen.
Anubis Poster
There is yet another egg in the Otacon's office. On the wall is a poster of Zone of the Enders: Anubis, which Otacon mentions during the cut scene. Fans of the game will recognize the poster as the game's box art.
Alexandra Roivas in a Girlie Mag
One of the girlie magazines you can pick up features Alexandra Roivas from Eternal Darkness. Just open the magazine and zoom in to see her in a bikini.
Get Peed On and Make Friends with Wolves
After fighting Psycho Mantis, follow Meryl through the wolf den. At the end of the den Meryl will be waiting with two wolves. Hit Meryl once and then quickly hide inside of a box. Meryl will instruct the pup to pee on Snake. You can now walk through the wolf den, while having the box equipped, without being attacked by the wolves.
Zone Of The Enders Reference
Look at one of the posters in Otacon's office to see the graphic from the front of the Zone of the Enders: The 2nd Runner box.
Eternal Darkness Reference
One of the magazines found in the game has a picture of Alexandra Roivas wearing a bikini. Pick it up, open it, then zoom in on the contents to find her.
Otacon's Costume
Successfully complete the game twice on any difficulty setting with submitting to Ocelot when being tortured to not save Meryl.
Otacon Demo
Successfully complete the game on any difficulty setting with submitting to Ocelot when being tortured to not save Meryl.
Meryl's Costume
Successfully complete the game twice on any difficulty setting without submitting to Ocelot when being tortured to save Meryl.
Meryl Demo
Successfully complete the game on any difficulty setting without submitting to Ocelot when being tortured to save Meryl.
Alternate Ending Theme
Successfully complete the game three times on any difficulty setting for an alternate ending theme.
Stealth Camouflage and Tuxedo Costume
Successfully complete the game twice on any difficulty setting to unlock the stealth camouflage and tuxedo costume. When you equip the stealth camouflage enemies (except bosses) and cameras will not detect you.
Bandana, Camera and Extreme Difficulty Setting
Successfully complete the game on any difficulty setting to unlock the Bandana, Camera, and extreme difficulty setting. When you equip the bandana you can use an unlimited amount of ammo and will not have to reload your gun. After you receive the camera there will be an "Album" option on the main menu, use this option to view pictures that have been taken.
Psycho Mantis Comments
Having saves from various games on your card such as Eternal Darkness, Legend of Zelda: The Wind Waker, Super Mario Sunshine, or Super Smash Bros. Melee will allow you to hear specific comments made by Psycho Mantis during the boss fight.
Gain Extra Health
During the Ninja boss fight, shoot the Mario figure on the desk to gain extra health.
Eternal Darkness Poster
In the Armory, B2 of the Tank Hangar, there are six separate rooms. If you go inside the top far right room, there is a locker with an Eternal Darkness game poster inside.
Outer Heaven Nametag
After the scene where the Ninja kills all the soldiers outside the Lab, Look at the soldier closest to the door. You have to look down using your scope, but his nametag says "Outer Heaven". You'll get a better camera angle if you look at it upsidedown.
Meryl in Her Panties
When in the Holding Cells area, crawling through the vents to find the DARPA Chief, you'll first see Meryl doing exercises in her cell. Before going forward to meet the DARPA Chief, exit the vent the same way you came in and re-enter to see Meryl doing exercises in her undewear. You can leave the vent and come back once again to see her performing other exercises.
Make Mei Ling Mad
Using your very cool and high tech codec call Mei Ling. When giving the option of saving or not select not saving. Do this a few times and eventually she'll give you a brief talking to and she'll stick her tongue out. Not very professional Mei Ling.
Upset Meryl
Right after you meet Meryl in the Restroom of the Nuke Building, Go into first person mode and stare at her breats. She will spit out comments like "Why are you staring at my...?" or "Don't look at me like that!"
Meryl